| Description : |
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
47.3 kDa |
| AA Sequence : |
MVQQTNNAENTEALLAGESSDSGAG LELGIASSPTPGSTASTGGKADDPS WCKTPSGHIKRPMNAFMVWSQIERR KIMEQSPDMHNAEISKRLGKRWKLL KDSDKIPFIREAERLRLKHMADYPD YKYRPRKKVKSGNANSSSSAAASSK PGEKGDKVGGSGGGGHGGGGGGGSS NAGGGGGGASGGGANSKPAQKKSCG SKVAGGAGGGVSKPHAKLILAGGGG GGKAAAAAAASFAAEQAGAAALLPL GAAADHHSLYKARTPSASASASSAA SASAALAAPGKHLAEKKVKRVYLFG GLGTSSSPVGGVGAGADPSDPLGLY EEEGAGCSPDAPSLSGRSSAASSPA AGRSPADHRGYASLRAASPAPSSAP SHASSSASSHSSSSSSSGSSSSDDE FEDDLLDLNPSSNFESMSLGSFSSS SALDRDLDFNFEPGSGSHFEFPDYC TPEVSEMISGDWLESSISNLVFTYS GPTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
