Recombinant Human SP1 protein, His & GST-tagged
| Cat.No. : | SP1-1956H |
| Product Overview : | Recombinant Human SP1 aa. (Leu260~Ala591) fused with N-terminal His & GST tag was produced in E. coli cells. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | GST&His |
| Protein Length : | Leu260~Ala591 |
| Description : | The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. |
| Form : | Freeze-dried powder |
| Molecular Mass : | 63kDa as determined by SDS-PAGE reducing conditions. |
| Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
| Purity : | >92% |
| Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Concentration : | 200μg/mL |
| Storage buffer : | PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300. |
| Reconstitution : | Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
| Isoelectric Point : | 5.6 |
| Gene Name | SP1 Sp1 transcription factor [ Homo sapiens (human) ] |
| Official Symbol | SP1 |
| Synonyms | SP1; Sp1 transcription factor; transcription factor Sp1; specificity protein 1 |
| Gene ID | 6667 |
| mRNA Refseq | NM_001251825.1 |
| Protein Refseq | NP_001238754.1 |
| UniProt ID | P08047 |
Not For Human Consumption!
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