Recombinant Human SP100
Cat.No. : | SP100-30988TH |
Product Overview : | Recombinant full length Human SP100, isoform A with N terminal proprietary tag, 78.87kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. |
Protein length : | 480 amino acids |
Molecular Weight : | 78.870kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Widely expressed. Sp100-B is expressed only in spleen, tonsil, thymus, mature B-cell line and some T-cell line, but not in brain, liver, muscle or non-lymphoid cell lines. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTE DQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRD RDLITNKMFEDSQDSCRNLVPVQRVVYNVLSELEKTFNLP VLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEE EREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPP ENGLSEHPCETEQINAKRKDTTSDKDDSLGSQQTNEQCAQ KAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPEAELH NHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQA SDIIVISSEDSEGSTDVDEPLEVFISAPRSEPVINNDNPL ESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVI GQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTST WRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGKED |
Sequence Similarities : | Contains 2 HMG box DNA-binding domains.Contains 1 HSR domain.Contains 1 SAND domain. |
Gene Name : | SP100 SP100 nuclear antigen [ Homo sapiens ] |
Official Symbol : | SP100 |
Synonyms : | SP100; SP100 nuclear antigen; nuclear antigen Sp100; nuclear autoantigen Sp-100; |
Gene ID : | 6672 |
mRNA Refseq : | NM_001080391 |
Protein Refseq : | NP_001073860 |
MIM : | 604585 |
Uniprot ID : | P23497 |
Chromosome Location : | 2q37.1 |
Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; |
Function : | chromo shadow domain binding; identical protein binding; kinase binding; protein binding; protein domain specific binding; |
Products Types
◆ Recombinant Protein | ||
SP100-202H | Recombinant Human SP100 Protein, His-tagged | +Inquiry |
SP100-201H | Recombinant Human SP100 Protein, GST-tagged | +Inquiry |
SP100-462H | Recombinant Human SP100 Protein, His-tagged | +Inquiry |
SP100-30989TH | Recombinant Human SP100 | +Inquiry |
Sp100-463M | Recombinant Mouse Sp100 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SP100-1674HCL | Recombinant Human SP100 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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