Recombinant Human SPATA18 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human SPATA18 Protein, Myc/DDK-tagged, C13 and N15-labeled

SPATA18 Related Products

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Cat.No. : SPATA18-650H
Product Overview : SPATA18 MS Standard C13 and N15-labeled recombinant protein (NP_660306) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 61.1 kDa
AA Sequence : MAENLKRLVS NETLRTLQEK LDFWLKEYNT NTCDQNLNHC LELIEQVAKV QGQLFGILTA AAQEGGRNDG VETIKSRLLP WLEASFTAAS LGKSVDSKVP SLQDTFDRER HKDPSPRDRD MQQLDSNLNS TRSQCNQVQD DLVETEKNLE ESKNRSAISL LAAEEEINQL KKQLKSLQAQ EDARHRNTDQ RSSENRRSEP WSLEERKREQ WNSLKQNADQ QDTEAMSDYK KQLRNLKEEI AVLSAEKSAL QGRSSRSRSP SPAPRSRSCS RSRSASPSTA VKVRRPSPNR SKLSNVARKA ALLSRFSDSY SQARLDAQCL LRRCIDKAET VQRIIYIATV EAFHVAKMAF RHFKIHVRKS LTPSYVGSND FENAVLDYVI CHLDLYDSQS SVNDVIRAMN VNPKISFPPV VDFCLLSDFI QEICCIAFAM QALEPPLDIA YGADGEVFND CKYRRSYDSD FTAPLVLYHV WPALMENDCV IMKGEAVTRR GAFWNSVRSV SRCRSRSLSP ICPRSQIGLN TMSRSRSPSP IRCGLPRFTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : SPATA18 spermatogenesis associated 18 [ Homo sapiens (human) ]
Official Symbol : SPATA18
Synonyms : SPATA18; spermatogenesis associated 18; Mieap; SPETEX1; mitochondria-eating protein; spermatogenesis associated 18 homolog; testis tissue sperm-binding protein Li 71n
Gene ID : 132671
mRNA Refseq : NM_145263
Protein Refseq : NP_660306
MIM : 612814
UniProt ID : Q8TC71

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