| Description : |
The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
37.5 kDa |
| AA Sequence : |
MGSASPGLSSVSPSHLLLPPDTVSR TGLEKAAAGAVGLERRDWSPSPPAT PEQGLSAFYLSYFDMLYPEDSSWAA KAPGASSREEPPEEPEQCPVIDSQA PAGSLDLVPGGLTLEEHSLEQVQSM VVGEVLKDIETACKLLNITADPMDW SPSNVQKWLLWTEHQYRLPPMGKAF QELAGKELCAMSEEQFRQRSPLGGD VLHAHLDIWKSAAWMKERTSPGAIH YCASTSEESWTDSEVDSSCSGQPIH LWQFLKELLLKPHSYGRFIRWLNKE KGIFKIEDSAQVARLWGIRKNRPAM NYDKLSRSIRQYYKKGIIRKPDISQ RLVYQFVHPITRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
