Recombinant Human SPRY4 protein, His-tagged

• Cat.No.: SPRY4-2326H
• Product Overview: Recombinant Human SPRY4(1-299aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-299 a.a.
• Description: SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
• Molecular Mass: 34.9 kDa (322aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEPPIPQ SAPLTPNSVM VQPLLDSRMS HSRLQHPLTI LPIDQVKTSH VENDYIDNPS LALTTGPKRTRGGAPELAPT PARCDQDVTH HWISFSGRPS SVSSSSSTSS DQRLLDHMAP PPVADQASPR AVRIQPKVVH CQPLDLKGPA VPPELDKHFLLCEACGKCKC KECASPRTLP SCWVCNQECL CSAQTLVNYG TCMCLVQGIF YHCTNEDDEG SCADHPCSCS RSNCCARWSF MGALSVVLPCLLCYLPATGC VKLAQRGYDR LRRPGCRCKH TNSVICKAAS GDAKTSRPDK PF
• Purity: > 85% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SPRY4 sprouty homolog 4 (Drosophila) [ Homo sapiens ]
• Official Symbol: SPRY4
• Synonyms: SPRY4; sprouty homolog 4 (Drosophila); protein sprouty homolog 4; spry-4
• Gene ID: 81848
• mRNA Refseq: NM_001127496
• Protein Refseq: NP_001120968
• MIM: 607984
• UniProt ID: Q9C004
• Chromosome Location: 5q31.3
• Pathway: Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem
• Function: protein binding