Recombinant Human SRSF10 Protein (1-183 aa), His-SUMO-tagged

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Recombinant Human SRSF10 Protein (1-183 aa), His-SUMO-tagged

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Cat.No. : SRSF10-990H
Product Overview : Recombinant Human SRSF10 Protein (1-183 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length of Isoform 3.
Description : Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Ses to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 38.2 kDa
Protein length : 1-183 aa
AA Sequence : MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRPNCSWN TQYSSAYYTS RKI
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : SRSF10 serine/arginine-rich splicing factor 10 [ Homo sapiens ]
Official Symbol : SRSF10
Synonyms : SRSF10; NSSR; SFRS13; SRp38; SRrp40; TASR1; TASR2; TASR; FUSIP1; FUSIP2; SFRS13A; FLJ30749; FLJ43846; DKFZp686H0644;
Gene ID : 10772
mRNA Refseq : NM_001191005
Protein Refseq : NP_001177934
MIM : 605221
UniProt ID : O75494

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