Recombinant Human SSX2B Protein, MYC/DDK-tagged

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Recombinant Human SSX2B Protein, MYC/DDK-tagged

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Cat.No. : SSX2B-2857H
Product Overview : Recombinant Human SSX2B protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 6757, located about 45 kb upstream in the opposite orientation on chromosome X.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 21.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : SSX2B SSX family member 2B [ Homo sapiens ]
Official Symbol : SSX2B
Synonyms : CT5.2; CT5.2b; HOM-MEL-40; SSX
Gene ID : 727837
mRNA Refseq : NM_001164417.2
Protein Refseq : NP_001157889

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