Recombinant Human STAT5A protein, His/MBP-tagged STAT5A-342H

Recombinant Human STAT5A protein, His/MBP-tagged

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Cat.No. : STAT5A-342H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human STAT5A(376-567 aa) fused with His/MBP tag was expressed in E. coli.
Description : The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.
Source : E. coli
Species : Human
Tag : His/MBP
Form : Liquid in PBS
Protein length : 376-567 aa
Purity : SDS-PAGE >90%
Applications : WB Positive Control
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : STAT5A signal transducer and activator of transcription 5A [ Homo sapiens ]
Official Symbol : STAT5A
Synonyms : STAT5A; signal transducer and activator of transcription 5A; STAT5; MGF;
Gene ID : 6776
mRNA Refseq : NM_003152
Protein Refseq : NP_003143
MIM : 601511
UniProt ID : P42229
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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