| Description : |
This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
82.6 kDa |
| AA Sequence : |
MNAAGIRAPEAAGADGTRLAPGGSP CLRRRGRPEESPAAVVAPRGAGELQ AAGAPLRFHPASPRRLHPASTPGPA WGWLLRRRRWAALLVLGLLVAGAAD GCELVPRHLRGRRATGSAATAASSP AAAAGDSPALMTDPCMSLSPPCFTE EDRFSLEALQTIHKQMDDDKDGGIE VEESDEFIREDMKYKDATNKHSHLH REDKHITIEDLWKRWKTSEVHNWTL EDTLQWLIEFVELPQYEKNFRDNNV KGTTLPRIAVHEPSFMISQLKISDR SHRQKLQLKALDVVLFGPLTRPPHN WMKDFILTVSIVIGVGGCWFAYTQN KTSKEHVAKMMKDLESLQTAEQSLM DLQERLEKAQEENRNVAVEKQNLER KMMDEINYAKEEACRLRELREGAEC ELSRRQYAEQELEQVRMALKKAEKE FELRSSWSVPDALQKWLQLTHEVEV QYYNIKRQNAEMQLAIAKDEAEKIK KKRSTVFGTLHVAHSSSLDEVDHKI LEAKKALSELTTCLRERLFRWQQIE KICGFQIAHNSGLPSLTSSLYSDHS WVVMPRVSIPPYPIAGGVDDLDEDT PPIVSQFPGTMAKPPGSLARSSSLC RSRRSIVPSSPQPQRAQLAPHAPHP SHPRHPHHPQHTPHSLPSPDPDILS VSSCPALYRNEEEEEAIYFSAEKQW EVPDTASECDSLNSSIGRKQSPPLS LEIYQTLSPRKISRDEVSLEDSSRG DSPVTVDVSWGSPDCVGLTETKSMI FSPASKVYNGILEKSCSMNQLSSGI PVPKPRHTSCSSAGNDSKPVQEAPS VARISSIPHDLCHNGEKSKKPSKIK SLFKKKSKTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
