Recombinant Human STING1 Protein (H232 variant), His-tagged
Cat.No. : | STING1-14H |
Product Overview : | Recombinant STING corresponding to amino acids 139-379 of human STING H232 allele (UniProtKB-Q86WV6) was expressed in E. coli cells and contains a His tag at the N-terminus. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Protein Length : | Leu139-Ser379 |
AA Sequence : | MGHHHHHHHHGSLAPAEISAVCEKG NFNVAHGLAWSYYIGYLRLILPELQ ARIRTYNQHYNNLLRGAVSQRLYIL LPLDCGVPDNLSMADPNIRFLDKLP QQTGDHAGIKDRVYSNSIYELLENG QRAGTCVLEYATPLQTLFAMSQYSQ AGFSREDRLEQAKLFCRTLEDILAD APESQNNCRLIAYQEPADDSSFSLS QEVLRHLRQEEKEEVTVGSLKTSAV PSTSTMSQEPELLISGMEKPLPLRT DFS |
Purity : | > 90% as analyzed by SDS-PAGE |
Notes : | This product is for laboratory research use only. |
Storage : | The product can be stored at -20 centigrade or below. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol, 2 mM DTT, 0.1% Tween 20 |
Gene Name : | STING1 stimulator of interferon response cGAMP interactor 1 [ Homo sapiens (human) ] |
Official Symbol : | STING1 |
Synonyms : | STING1; stimulator of interferon response cGAMP interactor 1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation; stimulator of interferon protein; transmembrane protein 173 |
Gene ID : | 340061 |
mRNA Refseq : | NM_198282 |
Protein Refseq : | NP_938023 |
MIM : | 612374 |
UniProt ID : | D6RID9 |
Products Types
◆ Recombinant Protein | ||
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STING1-024H | Recombinant Human STING1 Protein, His-tagged | +Inquiry |
STING1-15H | Recombinant Human STING1 Protein (R232 variant), His-tagged | +Inquiry |
STING1-137H | Recombinant Human STING1 H232 variant Protein, His-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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