| Description : |
Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
83.2 kDa |
| AA Sequence : |
MCSTNPGKWVTFDDDPAVQSSQKSK NFPLENQGVCRPNGLKLNLPGLREF PSGSSSTSSTPLSSPIVDFYFSPGP PSNSPLSTPTKDFPGFPGIPKAGTH VLYPIPESSSDSPLAISGGESSLLP TRPTCLSHALLPSDHSCTHPTPKVG LPDEVNPQQAESLGFQSDDLPQFQY FREDCAFSSPFWKDEGSDSHFTLDP PGSKKMFSSRNKEMPIDQKSLNKCS LNYICEKLEHLQSAENQDSLRSLSM HCLCAEENASSFVPHTLFRSQPKSG WSFMLRIPEKKNMMSSRQWGPIFLK VLPGGILQMYYEQGLEKPFKEIQLD PYCRLSEPKVENFSVAGKIHTVKIE HVSYTEKRKYHSKTEVVHEPDIEQM LKLGSTSYHDFLDFLTTVEEELMKL PAVSKPKKNYEEQEISLEIVDNFWG KVTKEGKFVESAVITQMYCLCFVNG NLECFLTLNDLELPKRDESYYEKDS EKKGIDILDYHFHKCVNVQEFEQSR IIKFVPLDACRFELMRFKTLYNGDN LPFSLKSVVVVQGAYVELQAFVNMA SLAQRSSYAGSLRSCDNIRIHFPVP SQWIKALWTMNLQRQKSLKAKMNRR ACLGSLQELESEPVIQVTVGSAKYE SAYQAVVWKIDRLPDKNSSLDHPHC LSYKLELGSDQEIPSDWYPFATVQF SVPDTCASRTEVRSLGVESDVQPQK HVQQRACYNIQVEIEKKWIKIDGED PDKIGDCITQTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
