Recombinant Human STXBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: STXBP1-3600H
• Product Overview: STXBP1 MS Standard C13 and N15-labeled recombinant protein (NP_001027392) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 67.6 kDa
• AA Sequence: MAPIGLKAVVGEKIMHDVIKKVKKK GEWKVLVVDQLSMRMLSSCCKMTDI MTEGITIVEDINKRREPLPSLEAVY LITPSEKSVHSLISDFKDPPTAKYR AAHVFFTDSCPDALFNELVKSRAAK VIKTLTEINIAFLPYESQVYSLDSA DSFQSFYSPHKAQMKNPILERLAEQ IATLCATLKEYPAVRYRGEYKDNAL LAQLIQDKLDAYKADDPTMGEGPDK ARSQLLILDRGFDPSSPVLHELTFQ AMSYDLLPIENDVYKYETSGIGEAR VKEVLLDEDDDLWIALRHKHIAEVS QEVTRSLKDFSSSKRMNTGEKTTMR DLSQMLKKMPQYQKELSKYSTHLHL AEDCMKHYQGTVDKLCRVEQDLAMG TDAEGEKIKDPMRAIVPILLDANVS TYDKIRIILLYIFLKNGITEENLNK LIQHAQIPPEDSEIITNMAHLGVPI VTDSTLRRRSKPERKERISEQTYQL SRWTPIIKDIMEDTIEDKLDTKHYP YISTRSSASFSTTAVSARYGHWHKN KAPGEYRSGPRLIIFILGGVSLNEM RCAYEVTQANGKWEVLIGSTHILTP QKLLDTLKKLNKTDEEISSTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: STXBP1 syntaxin binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: STXBP1
• Synonyms: STXBP1; syntaxin binding protein 1; syntaxin-binding protein 1; hUNC18; MUNC18 1; rbSec1; UNC18; N-Sec1; unc-18A; unc18-1; neuronal SEC1; protein unc-18 homolog 1; protein unc-18 homolog A; P67; NSEC1; RBSEC1; MUNC18-1; FLJ37475
• Gene ID: 6812
• mRNA Refseq: NM_001032221
• Protein Refseq: NP_001027392
• MIM: 602926
• UniProt ID: P61764