Recombinant Human SULF1 Protein, His tagged

• Cat.No.: SULF1-15H
• Product Overview: Purified recombinant protein of Human sulfatase 1 (SULF1), transcript variant 3, Gln487-Cys746, with N-terminal His tag, expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 487-746 aa
• Description: This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 30.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea
• Concentration: > 0.05 μg/μL as determined by microplate BCA method
• Shipping: Dry Ice

Gene Information

• Gene Name: SULF1 sulfatase 1 [ Homo sapiens (human) ]
• Official Symbol: SULF1
• Synonyms: SULF1; sulfatase 1; extracellular sulfatase Sulf-1; KIAA1077; SULF 1; sulfatase FP; SULF-1; HSULF-1; FLJ30905; FLJ38022; FLJ41750
• Gene ID: 23213
• mRNA Refseq: NM_015170
• Protein Refseq: NP_055985
• MIM: 610012
• UniProt ID: Q8IWU6