| Description : |
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
165.4 kDa |
| AA Sequence : |
MALSKGLRLLGRLGAEGDCSVLLEA RGRDDCLLFEAGTVATLAPEEKEVI KGQYGKLTDAYGCLGELRLKSGGTS LSFLVLVTGCTSVGRIPDAEIYKIT ATDFYPLQEEAKEEERLIALKKILS SGVFYFSWPNDGSRFDLTVRTQKQG DDSSEWGNSFFWNQLLHVPLRQHQV SCCDWLLKIICGVVTIRTVYASHKQ AKACLVSRVSCERTGTRFHTRGVND DGHVSNFVETEQMIYMDDGVSSFVQ IRGSVPLFWEQPGLQVGSHHLRLHR GLEANAPAFDRHMVLLKEQYGQQVV VNLLGSRGGEEVLNRAFKKLLWASC HAGDTPMINFDFHQFAKGGKLEKLE TLLRPQLKLHWEDFDVFTKGENVSP RFQKGTLRMNCLDCLDRTNTVQSFI ALEVLHLQLKTLGLSSKPIVDRFVE SFKAMWSLNGHSLSKVFTGSRALEG KAKVGKLKDGARSMSRTIQSNFFDG VKQEAIKLLLVGDVYGEEVADKGGM LLDSTALLVTPRILKAMTERQSEFT NFKRIRIAMGTWNVNGGKQFRSNVL RTAELTDWLLDSPQLSGATDSQDDS SPADIFAVGFEEMVELSAGNIVNAS TTNKKMWGEQLQKAISRSHRYILLT SAQLVGVCLYIFVRPYHVPFIRDVA IDTVKTGMGGKAGNKGAVGIRFQFH STSFCFICSHLTAGQSQVKERNEDY KEITQKLCFPMGRNVFSHDYVFWCG DFNYRIDLTYEEVFYFVKRQDWKKL LEFDQLQLQKSSGKIFKDFHEGAIN FGPTYKYDVGSAAYDTSDKCRTPAW TDRVLWWRKKHPFDKTAGELNLLDS DLDVDTKVRHTWSPGALQYYGRAEL QASDHRPVLAIVEVEVQEVDVGARE RVFQEVSSFQGPLDATVVVNLQSPT LEEKNEFPEDLRTELMQTLGSYGTI VLVRINQGQMLVTFADSHSALSVLD VDGMKVKGRAVKIRPKTKDWLKGLR EEIIRKRDSMAPVSPTANSCLLEEN FDFTSLDYESEGDILEDDEDYLVDE FNQPGVSDSELGGDDLSDVPGPTAL APPSKSPALTKKKQHPTYKDDADLV ELKRELEAVGEFRHRSPSRSLSVPN RPRPPQPPQRPPPPTGLMVKKSASD ASISSGTHGQYSILQTARLLPGAPQ QPPKARTGISKPYNVKQIKTTNAQE AEAAIRCLLEARGGASEEALSAVAP RDLEASSEPEPTPGAAKPETPQAPP LLPRRPPPRVPAIKKPTLRRTGKPL SPEEQFEQQTVHFTIGPPETSVEAP PVVTAPRVPPVPKPRTFQPGKAAER PSHRKPASDEAPPGAGASVPPPLEA PPLVPKVPPRRKKSAPAAFHLQVLQ SNSQLLQGLTYNSSDSPSGHPPAAG TVFPQGDFLSTSSATSPDSDGTKAM KPEAAPLLGDYQDPFWNLLHHPKLL NNTWLSKSSDPLDSGTRSPKRDPID PVSAGASAAKAELPPDHGHKTLGHW VTISDQEKRTALQVFDPLAKTSGPT RTRRLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
