Recombinant Human Syntaxin 12, His-tagged

• Cat.No.: STX12-6770H
• Product Overview: Recombinant humanSTX12 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Syntaxin 12, alsoknown as, belongs to the syntaxin family. Syntaxin family is cellularreceptors for transport vesicles which participate in exocytosis inneutrophils. STX12 regulates protein transport between late endosomes and thetrans-Golgi network and interacts with ABC1 (ATP-binding cassette transporterA1), a protein that facilitates cellular release of choline-phospholipids andcholesterol to apoA-I (apolipoprotein A-I)
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,1mM DTT
• Molecular Weight: 31.0 kDa (272aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS -PAGE
• Concentration: 0.5 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMSYGPL DMYRNPGPSG PQLRDFSSII QTCSGNIQRI SQATAQIKNL MSQLGTKQDSSKLQENLQQLQHSTNQLAKE TNELLKELGS LPLPLSTSEQ RQQRLQKERL MNDFSAALNN FQAVQRRVSEKEKESIARAR AGSRLSAEER QREEQLVSFD SHEEWNQMQS QEDEVAITEQ DLELIKERET AIRQLEADILDVNQIFKDLA MMIHDQGDLI DSIEANVESS EVHVERATEQ LQRAAYYQKK SR
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles

Gene Information

• Gene Name: STX12syntaxin 12 [ Homo sapiens ]
• Official Symbol: STX12
• Synonyms: STX12; syntaxin 12; syntaxin-12;STX13; STX14; STX12; STX13; STX14
• Gene ID: 23673
• mRNA Refseq: NM_177424
• Protein Refseq: NP_803173
• MIM: 606892
• Uniprot ID: Q86Y82
• Chromosome Location: 1p35.3
• Pathway: Botulinum neurotoxicity,organism-specific biosystem; Neuronal System, organism-specific biosystem;Phagosome, organism-specific biosystem; Phagosome, conserved biosystem;Proteolytic cleavage of SNARE complex proteins, organism-specific biosystem
• Function: SNAP receptor activity; proteinbinding