Recombinant Human TACSTD2 protein, Fc-tagged TACSTD2-416H

Recombinant Human TACSTD2 protein, Fc-tagged

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Recombinant Human TACSTD2 protein, Fc-tagged

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Cat.No. : TACSTD2-416H
Product Overview : Recombinant Human TACSTD2 protein (His27-Thr274) was fused to human IgG1 Fc tag at the C-terminus and expressed in human 293 cells (HEK293).
Description : TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
Source : HEK293
Species : Human
Tag : human IgG1 Fc
Predicted N Terminal : His27
Form : Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 54.3 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : His27-Thr274
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
SDS-PAGE of TACSTD2-416H :

Human TROP-2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Gene Name : TACSTD2
Official Symbol : TACSTD2
Synonyms : EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Gene ID : 4070
mRNA Refseq : NM_002353.3
Protein Refseq : NP_002344.2
MIM : 137290
UniProt ID : P09758

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