Recombinant Human TAGLN protein, MYC/DDK-tagged

• Cat.No.: TAGLN-302H
• Product Overview: Recombinant Human TAGLN, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 22.4 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TAGLN transgelin [ Homo sapiens ]
• Official Symbol: TAGLN
• Synonyms: TAGLN; transgelin; DKFZp686P11128; SM22; SM22 alpha; SMCC; TAGLN1; transgelin variant 2; WS3 10; SM22-alpha; 22 kDa actin-binding protein; smooth muscle protein 22-alpha; WS3-10; DKFZp686B01212
• Gene ID: 6876
• mRNA Refseq: NM_001001522
• Protein Refseq: NP_001001522
• MIM: 600818
• UniProt ID: Q01995
• Chromosome Location: 11q23.2
• Function: actin binding