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Recombinant Human Tau-441 (2N4R) Wild-Type Protein (Pre-formed Fibrils)

Cat.No. : MAPT-13H
Product Overview : Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils without tag was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Source : E.coli
Species : Human
Protein Length : Full Length
AA Sequence : MAEPRQEFEVMEDHAGTYGLGDRKD QGGYTMHQDQEGDTDAGLKESPLQT PTEDGSEEPGSETSDAKSTPTAEDV TAPLVDEGAPGKQAAAQPHTEIPEG TTAEEAGIGDTPSLEDEAAGHVTQA RMVSKSKDGTGSDDKKAKGADGKTK IATPRGAAPPGQKGQANATRIPAKT PPAPKTPPSSGEPPKSGDRSGYSSP GSPGTPGSRSRTPSLPTPPTREPKK VAVVRTPPKSPSSAKSRLQTAPVPM PDLKNVKSKIGSTENLKHQPGGGKV QIINKKLDLSNVQSKCGSKDNIKHV PGGGSVQIVYKPVDLSKVTSKCGSL GNIHHKPGGGQVEVKSEKLDFKDRV QSKIGSLDNITHVPGGGNKKIETHK LTFRENAKAKTDHGAEIVYKSPVVS GDTSPRHLSNVSSTGSIDMVDSPQL ATLADEVSASLAKQGL
Purity : > 95%
Applications : WB, SDS-PAGE, In vivo assay, In vitro assay
Storage : At -80 centigrade
Storage Buffer : 10 mM HEPES, 100 mM NaCl pH 7.4
Shipping : Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
Gene Name : MAPT microtubule associated protein tau [ Homo sapiens (human) ]
Official Symbol : MAPT
Synonyms : Active tau PFFs, tau PFF, active tau protein Pre-formed Fibrils, active tau aggregates, microtubule-associated protein tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit, MAPT DeltaK280, ΔK280 tau, K18 delta K280 tau, truncated ΔK280 tau; MAPT; microtubule associated protein tau; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6; microtubule-associated protein tau; G protein beta1/gamma2 subunit-interacting factor 1; PHF-tau; Tau-derived paired helical filament hexapeptide; neurofibrillary tangle protein; paired helical filament-tau; protein phosphatase 1, regulatory subunit 103
Gene ID : 4137
mRNA Refseq : NM_016841
Protein Refseq : NP_058525
MIM : 157140
UniProt ID : P10636

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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