Recombinant Human TBC1D10C Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TBC1D10C-5512H
• Product Overview: TBC1D10C MS Standard C13 and N15-labeled recombinant protein (NP_940919) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 49.7 kDa
• AA Sequence: MAQALGEDLVQPPELQDDSSSLGSD SELSGPGPYRQADRYGFIGGSSAEP GPGHPPADLIRQREMKWVEMTSHWE KTMSRRYKKVKMQCRKGIPSALRAR CWPLLCGAHVCQKNSPGTYQELAEA PGDPQWMETIGRDLHRQFPLHEMFV SPQGHGQQGLLQVLKAYTLYRPEQG YCQAQGPVAAVLLMHLPPEEAFWCL VQICEVYLPGYYGPHMEAVRLDAEV FMALLRRLLPHVHKHLQQVGVGPLL YLPEWFLCLFARSLPFPTVLRVWDA FLSEGARVLFRVGLTLVRLALGTAE QRGACPGLLETLGALRAIPPAQLQE EAFMSQVHSVVLSERDLQREIKAQL AQLPDSAPGPPPRPQVRLAGAQAIF EAQQLAGVRRGAKPEVPRIVVQPPE EPRPPRRKPQTRGKTFHGLLTRARG PPIEGPPRPQRGSTSFLDTRFTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TBC1D10C TBC1 domain family member 10C [ Homo sapiens (human) ]
• Official Symbol: TBC1D10C
• Synonyms: TBC1D10C; TBC1 domain family, member 10C; carabin; Carabin; EPI64C; FLJ00332; CARABIN; MGC46488
• Gene ID: 374403
• mRNA Refseq: NM_198517
• Protein Refseq: NP_940919
• MIM: 610831
• UniProt ID: Q8IV04