Recombinant Human TBC1D2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TBC1D2 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : TBC1D2-2575H
Product Overview : TBC1D2 MS Standard C13 and N15-labeled recombinant protein (NP_060891) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 103.9 kDa
AA Sequence : MEGAGENAPE SSSSAPGSEE SARDPQVPPP EEESGDCARS LEAVPKKLCG YLSKFGGKGP IRGWKSRWFF YDERKCQLYY SRTAQDANPL DSIDLSSAVF DCKADAEEGI FEIKTPSRVI TLKAATKQAM LYWLQQLQMK RWEFHNSPPA PPATPDAALA GNGPVLHLEL GQEEAELEEF LCPVKTPPGL VGVAAALQPF PALQNISLKH LGTEIQNTMH NIRGNKQAQG TGHEPPGEDS PQSGEPQREE QPLASDASTP GREPEDSPKP APKPSLTISF AQKAKRQNNT FPFFSEGITR NRTAQEKVAA LEQQVLMLTK ELKSQKELVK ILHKALEAAQ QEKRASSAYL AAAEDKDRLE LVRHKVRQIA ELGRRVEALE QERESLAHTA SLREQQVQEL QQHVQLLMDK NHAKQQVICK LSEKVTQDFT HPPDQSPLRP DAANRDFLSQ QGKIEHLKDD MEAYRTQNCF LNSEIHQVTK IWRKVAEKEK ALLTKCAYLQ ARNCQVESKY LAGLRRLQEA LGDEASECSE LLRQLVQEAL QWEAGEASSD SIELSPISKY DEYGFLTVPD YEVEDLKLLA KIQALESRSH HLLGLEAVDR PLRERWAALG DLVPSAELKQ LLRAGVPREH RPRVWRWLVH LRVQHLHTPG CYQELLSRGQ AREHPAARQI ELDLNRTFPN NKHFTCPTSS FPDKLRRVLL AFSWQNPTIG YCQGLNRLAA IALLVLEEEE SAFWCLVAIV ETIMPADYYC NTLTASQVDQ RVLQDLLSEK LPRLMAHLGQ HHVDLSLVTF NWFLVVFADS LISNILLRVW DAFLYEGTKY NEKEILRLQN GLEIYQYLRF FTKTISNSRK LMNIAFNDMN PFRMKQLRQL RMVHRERLEA ELRELEQLKA EYLERRASRR RAVSEGCASE DEVEGEATRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TBC1D2 TBC1 domain family member 2 [ Homo sapiens (human) ]
Official Symbol : TBC1D2
Synonyms : TBC1D2; TBC1 domain family, member 2; TBC1 domain family member 2A; Armus; PARIS1; prostate antigen recognized and identified by SEREX; TBC1D2A; armus; TBC1 domain family, member 2A; prostate antigen recognized and identified by SEREX 1; PARIS-1; FLJ10702; FLJ16244; FLJ42782; DKFZp761D1823;
Gene ID : 55357
mRNA Refseq : NM_018421
Protein Refseq : NP_060891
MIM : 609871
UniProt ID : Q9BYX2

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