Recombinant Human TBCE Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TBCE Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : TBCE-4632H
Product Overview : TBCE MS Standard C13 and N15-labeled recombinant protein (NP_003184) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 59.3 kDa
AA Sequence : MSDTLTADVI GRRVEVNGEH ATVRFAGVVP PVAGPWLGVE WDNPERGKHD GSHEGTVYFK CRHPTGGSFI RPNKVNFGTD FLTAIKNRYV LEDGPEEDRK EQIVTIGNKP VETIGFDSIM KQQSQLSKLQ EVSLRNCAVS CAGEKGGVAE ACPNIRKVDL SKNLLSSWDE VIHIADQLRH LEVLNVSENK LKFPSGSVLT GTLSVLKVLV LNQTGITWAE VLRCVAGCPG LEELYLESNN IFISERPTDV LQTVKLLDLS SNQLIDENQL YLIAHLPRLE QLILSDTGIS SLHFPDAGIG CKTSMFPSLK YLVVNDNQIS QWSFFNELEK LPSLRALSCL RNPLTKEDKE AETARLLIIA SIGQLKTLNK CEILPEERRR AELDYRKAFG NEWKQAGGHK DPEKNRLSEE FLTAHPRYQF LCLKYGAPED WELKTQQPLM LKNQLLTLKI KYPHQLDQKV LEKQLPGSMT IQKVKGLLSR LLKVPVSDLL LSYESPKKPG REIELENDLK SLQFYSVENG DCLLVRWTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TBCE tubulin folding cofactor E [ Homo sapiens (human) ]
Official Symbol : TBCE
Synonyms : TBCE; tubulin folding cofactor E; KCS, Kenny Caffey syndrome, tubulin specific chaperone e; tubulin-specific chaperone E; HRD; KCS1; pac2; Kenny-Caffey syndrome; tubulin-folding cofactor E; KCS;
Gene ID : 6905
mRNA Refseq : NM_003193
Protein Refseq : NP_003184
MIM : 604934
UniProt ID : Q15813

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