Recombinant Human TBCK Protein, GST-tagged

• Cat.No.: TBCK-4350H
• Product Overview: Human MGC16169 full-length ORF ( NP_149106.2, 1 a.a. - 830 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 120.1 kDa
• AA Sequence: MFPLKDAEMGAFTFFASALPHDVCG SNGLPLTPNSIKILGRFQILKTITH PRLCQYVDISRGKHERLVVVAEHCE RSLEDLLRERKPVRYPSYLAPEVIA QGIFKTTDHMPSKKPLPSGPKSDVW SLGIILFELCVGRKLFQSLDISERL KFLLTLDCVDDTLIVLAEEHGCLDI IKELPETVIDLLNKCLTFHPSKRPT PDELMKDKVFSEVSPLYTPFTKPAS LFSSSLRCADLTLPEDISQLCKDIN NDYLAERSIEEVYYLWCLAGGDLEK ELVNKEIIRSKPPICTLPNFLFEDG ESFGQGRDRSSLLDDTTVTLSLCQL RNRLKDVGGEAFYPLLEDDQSNLPH SNSNNELSAAATLPLIIREKDTEYQ LNRIILFDRLLKAYPYKKNQIWKEA RVDIPPLMRGLTWAALLGVEGAIHA KYDAIDKDTPIPTDRQIEVDIPRCH QYDELLSSPEGHAKFRRVLKAWVVS HPDLVYWQGLDSLCAPFLYLNFNNE ALAYACMSAFIPKYLYNFFLKDNSH VIQEYLTVFSQMIAFHDPELSNHLN EIGFIPDLYAIPWFLTMFTHVFPLH KIFHLWDTLLLGNSSFPFCIGVAIL QQLRDRLLANGFNECILLFSDLPEI DIERCVRESINLFCWTPKSATYRQH AQPPKPSSDSSGGRSSAPYFSAECP DPPKTDLSRESIPLNDLKSEVSPRI SAEDLIDLCELTVTGHFKTPSKKTK SSKPKLLVVDIRNSEDFIRGHISGS INIPFSAAFTAEGELTQGPYTAMLQ NFKGKVIVIVGHVAKHTAEFAAHLV KMKYPRICILDGGINKIKPTGLLTI PSPQI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: TBCK TBC1 domain containing kinase [ Homo sapiens (human) ]
• Official Symbol: TBCK
• Synonyms: TBCK; TBC1 domain containing kinase; TBCKL; IHPRF3; HSPC302; TBC domain-containing protein kinase-like protein
• Gene ID: 93627
• mRNA Refseq: NM_001163435
• Protein Refseq: NP_001156907
• MIM: 616899
• UniProt ID: Q8TEA7