Recombinant Human TBXAS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TBXAS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : TBXAS1-2371H
Product Overview : TBXAS1 MS Standard C13 and N15-labeled recombinant protein (NP_001124438) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 60.6 kDa
AA Sequence : MMEALGFLKL EVNGPMVTVA LSVALLALLK WYSTSAFSRL EKLGLRHPKP SPFIGNLTFF RQGFWESQME LRKLYGPLCG YYLGRRMFIV ISEPDMIKQV LVENFSNFTN RMASGLEFKS VADSVLFLRD KRWEEVRGAL MSAFSPEKLN EMVPLISQAC DLLLAHLKRY AESGDAFDIQ RCYCNYTTDV VASVAFGTPV DSWQAPEDPF VKHCKRFFEF CIPRPILVLL LSFPSIMVPL ARILPNKNRD ELNGFFNKLI RNVIALRDQQ AAEERRRDFL QMVLDARHSA SPMGVQDFDI VRDVFSSTGC KPNPSRQHQP SPMARPLTVD EIVGQAFIFL IAGYEIITNT LSFATYLLAT NPDCQEKLLR EVDVFKEKHM APEFCSLEEG LPYLDMVIAE TLRMYPPAFR FTREAAQDCE VLGQRIPAGA VLEMAVGALH HDPEHWPSPE TFNPERFTAE ARQQHRPFTY LPFGAGPRSC LGVRLGLLEV KLTLLHVLHK FRFQACPETQ VPLQLESKSA LGPKNGVYIK IVSRTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TBXAS1 thromboxane A synthase 1 [ Homo sapiens (human) ]
Official Symbol : TBXAS1
Synonyms : TBXAS1; thromboxane A synthase 1 (platelet); thromboxane A synthase 1 (platelet, cytochrome P450, subfamily V); thromboxane-A synthase; CYP5; CYP5A1; cytochrome P450; family 5; subfamily A; polypeptide 1; THAS; TS; TXAS; TXS; TXA synthase; cytochrome P450 5A1; platelet, cytochrome P450, subfamily V; cytochrome P450, family 5, subfamily A, polypeptide 1; thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A); GHOSAL; BDPLT14; FLJ52771;
Gene ID : 6916
mRNA Refseq : NM_001130966
Protein Refseq : NP_001124438
MIM : 274180
UniProt ID : P24557

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