Recombinant Human TCAP Protein, His-tagged

• Cat.No.: TCAP-414H
• Product Overview: Recombinant human TCAP protein, fused to His tag at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
• Molecular Mass: 18.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: titin-cap [ Homo sapiens ]
• Official Symbol: TCAP
• Synonyms: CMD1N; CMH25; LGMD2G; T-cap; TELE; telethonin
• Gene ID: 8557
• mRNA Refseq: NM_003673.3
• Protein Refseq: NP_003664.1
• MIM: 604488
• UniProt ID: O15273