"TDH" Related Products

Recombinant Human TDH protein, His & GST-tagged

Cat.No. : TDH-1749H
Product Overview : Recombinant Human TDH aa. (Met1~Cys229 (Accession # Q8IZJ6)) fused with N-terminal His & GST tag was produced in E. coli cells.
Description : This gene appears to be an evolving pseudogene of L-threonine 3-dehydrogenase (TDH). In both prokaryotes and eukaryotes, TDH catalyzes the first of two steps in one of two L-threonine degradation pathways. However, in human, the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins. This suggests that the human gene is therefore a pseudogene. Transcripts of this gene are found in all tissues and alternatively spliced transcripts have been described. It is not known if these transcripts are translated, or if the possible protein product provides any functional role.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 55.3kDa
Protein length : Met1~Cys229 (Accession # Q8IZJ6)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Isoelectric Point : 9.6
SDS-PAGE :

Gene Name : TDH L-threonine dehydrogenase (pseudogene) [ Homo sapiens (human) ]
Official Symbol : TDH
Synonyms : TDH; L-threonine dehydrogenase (pseudogene); SDR14E1P
Gene ID : 157739
UniProt ID : Q8IZJ6

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