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Recombinant Human TDP1 Protein, Flag-tagged

Cat.No. : TDP1-3327H
Product Overview : Recombinant Human TDP1 Protein, Transcript Variant 2, is produced by HEK293T expression system. This protein is fused with a Flag tag.
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Description : The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).
Source : HEK293 cells
Species : Human
Tag : Flag
Form : PBS buffer
Molecular Mass : 68 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Gene Name : TDP1 tyrosyl-DNA phosphodiesterase 1 [ Homo sapiens ]
Official Symbol : TDP1
Synonyms : TDP1; tyrosyl-DNA phosphodiesterase 1; FLJ11090; SCAN1; tyr-DNA phosphodiesterase 1; MGC104252;
Gene ID : 55775
mRNA Refseq : NM_001008744
Protein Refseq : NP_001008744
MIM : 607198
UniProt ID : Q9NUW8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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