Recombinant Human TEAD1 protein, His-Avi-tagged

• Cat.No.: TEAD1-4584H
• Product Overview: Recombinant Human TEAD1 protein(P28347)(1-426aa), fused to N-terminal His tag and Avi tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His&Avi
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 51.3 kDa
• Protein length: 1-426aa
• AA Sequence: MEPSSWSGSESPAENMERMSDSADK PIDNDAEGVWSPDIEQSFQEALAIY PPCGRRKIILSDEGKMYGRNELIAR YIKLRTGKTRTRKQVSSHIQVLARR KSRDFHSKLKDQTAKDKALQHMAAM SSAQIVSATAIHNKLGLPGIPRPTF PGAPGFWPGMIQTGQPGSSQDVKPF VQQAYPIQPAVTAPIPGFEPASAPA PSVPAWQGRSIGTTKLRLVEFSAFL EQQRDPDSYNKHLFVHIGHANHSYS DPLLESVDIRQIYDKFPEKKGGLKE LFGKGPQNAFFLVKFWADLNCNIQD DAGAFYGVTSQYESSENMTVTCSTK VCSFGKQVVEKVETEYARFENGRFV YRINRSPMCEYMINFIHKLKHLPEK YMMNSVLENFTILLVVTNRDTQETL LCMACVFEVSNSEHGAQHHIYRLVK D
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) [ Homo sapiens ]
• Official Symbol: TEAD1
• Synonyms: TEAD1; TEA domain family member 1 (SV40 transcriptional enhancer factor); AA, atrophia areata, peripapillary chorioretinal degeneration , TCF13; transcriptional enhancer factor TEF-1; TEF 1; protein GT-IIC; transcription factor 13; transcriptional enhancer factor 1; AA; REF1; TCF13; TEF-1; NTEF-1; TCF-13; TEAD-1; FLJ17970
• Gene ID: 7003
• mRNA Refseq: NM_021961
• Protein Refseq: NP_068780
• MIM: 189967
• UniProt ID: P28347

Reviews

03/05/2020

Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.

01/16/2020

Its usage in ELISA and protein electron microscopy structure analysis has been reported to yield highly reproducible and interpretable results, providing valuable insights into the molecular mechanisms and biological processes under investigation.

08/31/2019

Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.

Q&As

Are there any clinical trials targeting TEAD1 in cancer treatment?

Yes, there are ongoing clinical trials exploring the inhibition of TEAD1 in cancer therapy.

How does TEAD1 impact skeletal muscle development and regeneration?

TEAD1 regulates genes involved in skeletal muscle development and regeneration.

Does TEAD1 have any connection to neurological disorders?

TEAD1 has been implicated in neurodevelopmental disorders, and it may be a target for further research in this area.

Can TEAD1 be used as a biomarker for cancer diagnosis or prognosis?

TEAD1 expression levels have been associated with cancer prognosis, and it can serve as a potential biomarker.

Are there any therapeutic strategies targeting TEAD1 in cardiac diseases?

Research is ongoing to develop therapies that target TEAD1 in cardiac conditions.