Recombinant Human TEAD2 Protein, His-tagged
Cat.No. : | TEAD2-08H |
Product Overview : | Human TEAD2 (aa217-447), with C-terminal His-tag, was expressed from E.coli and purified by a three-step chromatographic procedure comprising affinity, ion exchange and gel filtration chromatography steps. |
- Specification
- Gene Information
- Related Products
Description : | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 29.7 kDa |
Purity : | >95% |
Storage Buffer : | 20 mM TRIS/HCl pH 8.0, 100 mM NaCl, 2 mM MgCl2, 1 mM TCEP, 5% glycerol |
Gene Name : | TEAD2 TEA domain transcription factor 2 [ Homo sapiens (human) ] |
Official Symbol : | TEAD2 |
Synonyms : | TEAD2; TEA domain transcription factor 2; ETF; TEF4; TEF-4; TEAD-2; transcriptional enhancer factor TEF-4; TEA domain family member 2 |
Gene ID : | 8463 |
mRNA Refseq : | NM_001256658 |
Protein Refseq : | NP_001243587 |
MIM : | 601729 |
UniProt ID : | Q15562 |
Products Types
◆ Recombinant Protein | ||
TEAD2-9115M | Recombinant Mouse TEAD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TEAD2-33H | Recombinant Human TEAD2 protein, His-tagged | +Inquiry |
TEAD2-35H | Recombinant Human TEAD2 protein, His-Myc-tagged | +Inquiry |
TEAD2-32H | Recombinant Human TEAD2 protein, GST-tagged | +Inquiry |
TEAD1-02H | Recombinant human TEA domain transcription factor 1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
TEAD2-1757HCL | Recombinant Human TEAD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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