Recombinant Human TET2 Protein, FLAG/His-tagged TET2-01H

Recombinant Human TET2 Protein, FLAG/His-tagged

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Recombinant Human TET2 Protein, FLAG/His-tagged

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Cat.No. : TET2-01H
Product Overview : Recombinant human TET2 protein (a.a. 1129-2002 (end)) with N-terminal FLAG tag and C-terminal His tag was expressed in Sf9 cells via a baculovirus expression system.
Description : The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
Source : Insects Cell
Species : Human
Tag : FLAG/His
Molecular Mass : 100 kDa
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage : At least 6 months at –80 centigrade. Avoid freeze/thaw cycles.
Concentration : 0.81 mg/mL
Storage Buffer : 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, 3 mM DTT and 400 mM imidazole.
Gene Name : TET2 tet methylcytosine dioxygenase 2 [ Homo sapiens (human) ]
Official Symbol : TET2
Synonyms : TET2; tet methylcytosine dioxygenase 2; MDS; KIAA1546; methylcytosine dioxygenase TET2; probable methylcytosine dioxygenase TET2; tet oncogene family member 2; EC 1.14.11.n2
Gene ID : 54790
mRNA Refseq : NM_001127208
Protein Refseq : NP_001120680
MIM : 612839
UniProt ID : Q6N021

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