Recombinant Human TFB2M Protein, Myc/DDK-tagged, C13 and N15-labeled
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
| Cat.No. : | TFB2M-696H |
| Product Overview : | TFB2M MS Standard C13 and N15-labeled recombinant protein (NP_071761) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Stimulates transcription independently of the methyltransferase activity. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 45.3 kDa |
| AA Sequence : | MWIPVVGLPR RLRLSALAGA GRFCILGSEA ATRKHLPARN HCGLSDSSPQ LWPEPDFRNP PRKASKASLD FKRYVTDRRL AETLAQIYLG KPSRPPHLLL ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD FFKLDPRSGG VIKPPAMSSR GLFKNLGIEA VPWTADIPLK VVGMFPSRGE KRALWKLAYD LYSCTSIYKF GRIEVNMFIG EKEFQKLMAD PGNPDLYHVL SVIWQLACEI KVLHMEPWSS FDIYTRKGPL ENPKRRELLD QLQQKLYLIQ MIPRQNLFTK NLTPMNYNIF FHLLKHCFGR RSATVIDHLR SLTPLDARDI LMQIGKQEDE KVVNMHPQDF KTLFETIERS KDCAYKWLYD ETLEDRTRTR PLEQKLISEE DLAANDILDY KDDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
|
| Gene Name : | TFB2M transcription factor B2, mitochondrial [ Homo sapiens (human) ] |
| Official Symbol : | TFB2M |
| Synonyms : | TFB2M; transcription factor B2, mitochondrial; dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; Hkp1; hTFB2M; h-mtTFB; h-mtTFB2; HCV NS5A-transactivated protein 5; mitochondrial 12S rRNA dimethylase 2; mitochondrial transcription factor B2; hepatitis C virus NS5A-transactivated protein 5; S-adenosylmethionine-6-N, N-adenosyl(rRNA) dimethyltransferase 2; mtTFB2; |
| Gene ID : | 64216 |
| mRNA Refseq : | NM_022366 |
| Protein Refseq : | NP_071761 |
| MIM : | 607055 |
| UniProt ID : | Q9H5Q4 |
◆ Recombinant Protein
| Tfb2m-1131M | Recombinant Mouse Tfb2m Protein, MYC/DDK-tagged | +Inquiry |
| TFB2M-3195H | Recombinant Human TFB2M, His-tagged | +Inquiry |
| TFB2M-6026R | Recombinant Rat TFB2M Protein | +Inquiry |
| TFB2M-6345Z | Recombinant Zebrafish TFB2M | +Inquiry |
| TFB2M-1580H | Recombinant Human TFB2M protein | +Inquiry |
|
|
◆ Lysates
| TFB2M-1135HCL | Recombinant Human TFB2M 293 Cell Lysate | +Inquiry |
|
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy
