Recombinant Human TFEC Protein, His-tagged

• Cat.No.: TFEC-464H
• Product Overview: Recombinant Human TFEC, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: THis gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for tHis gene.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 35.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TFEC transcription factor EC [ Homo sapiens ]
• Official Symbol: TFEC
• Synonyms: TFEC; transcription factor EC; bHLHe34; TCFEC; TFECL; transcription factor EC-like; class E basic helix-loop-helix protein 34; TFE-C; TFEC-L; hTFEC-L
• Gene ID: 22797
• mRNA Refseq: NM_001018058
• Protein Refseq: NP_001018068
• MIM: 604732
• UniProt ID: O14948