Recombinant Human TFRC Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TFRC-791H
• Product Overview: TFRC MS Standard C13 and N15-labeled recombinant protein (NP_003225) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 84.7 kDa
• AA Sequence: MMDQARSAFSNLFGGEPLSYTRFSL ARQVDGDNSHVEMKLAVDEEENADN NTKANVTKPKRCSGSICYGTIAVIV FFLIGFMIGYLGYCKGVEPKTECER LAGTESPVREEPGEDFPAARRLYWD DLKRKLSEKLDSTDFTGTIKLLNEN SYVPREAGSQKDENLALYVENQFRE FKLSKVWRDQHFVKIQVKDSAQNSV IIVDKNGRLVYLVENPGGYVAYSKA ATVTGKLVHANFGTKKDFEDLYTPV NGSIVIVRAGKITFAEKVANAESLN AIGVLIYMDQTKFPIVNAELSFFGH AHLGTGDPYTPGFPSFNHTQFPPSR SSGLPNIPVQTISRAAAEKLFGNME GDCPSDWKTDSTCRMVTSESKNVKL TVSNVLKEIKILNIFGVIKGFVEPD HYVVVGAQRDAWGPGAAKSGVGTAL LLKLAQMFSDMVLKDGFQPSRSIIF ASWSAGDFGSVGATEWLEGYLSSLH LKAFTYINLDKAVLGTSNFKVSASP LLYTLIEKTMQNVKHPVTGQFLYQD SNWASKVEKLTLDNAAFPFLAYSGI PAVSFCFCEDTDYPYLGTTMDTYKE LIERIPELNKVARAAAEVAGQFVIK LTHDVELNLDYERYNSQLLSFVRDL NQYRADIKEMGLSLQWLYSARGDFF RATSRLTTDFGNAEKTDRFVMKKLN DRVMRVEYHFLSPYVSPKESPFRHV FWGSGSHTLPALLENLKLRKQNNGA FNETLFRNQLALATWTIQGAANALS GDVWDIDNEFTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TFRC transferrin receptor [ Homo sapiens (human) ]
• Official Symbol: TFRC
• Synonyms: TFRC; transferrin receptor (p90, CD71); transferrin receptor protein 1; CD71; TFR1; T9; TR; TFR; p90; TRFR
• Gene ID: 7037
• mRNA Refseq: NM_003234
• Protein Refseq: NP_003225
• MIM: 190010
• UniProt ID: P02786