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Recombinant Human TGFB1 protein, Avi-tagged

Cat.No. : TGFB1-364H
Product Overview : Human Mature TGF beta 1 Protein is expressed from mammalian with Avi Tag at the C-terminal. It contains Ala279-Ser390.
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Description : TGF-beta 1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure. TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition.Transforming growth factor beta-1 is multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration.
Source : HEK293
Species : Human
Tag : Avi
Form : Lyophilized from 0.22um filtered solution in 50mM Glycine,150mM NaCl (pH2.5).
Molecular Mass : The protein has a predicted MW of 13.2 KDa. Due to glycosylation, the protein migrates to 13-14KDa based on Bis-Tris PAGE result.
Protein length : Ala279-Ser390
Endotoxin : Less than 0.01EU per ug by the LAL method.
Purity : > 95% as determined by SDS-PAGE
Storage : The product should be stored at -70°C or -20°C.
Gene Name : TGFB1
Official Symbol : TGFB1
Synonyms : Transforming growth factor beta-1, CEDLAP; DPD1; TGF beta1; TGFB; TGFB1; TGF-beta 1 protein; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1; transforming growth factor beta-1;
Gene ID : 7040
mRNA Refseq : NM_000660.7
Protein Refseq : NP_000651.3
MIM : 190180
UniProt ID : P01137

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is TGFB1 involved in bone remodeling? 08/04/2020

TGFB1 stimulates the activity of cells involved in bone formation (osteoblasts) and plays a role in regulating bone resorption by influencing osteoclast function.

Are there any side effects associated with therapies targeting TGFB1? 10/09/2019

Potential side effects of anti-TGFB1 therapies may include immune system suppression, gastrointestinal issues, and skin reactions.

Can TGFB1 be used as a biomarker for certain diseases? 04/11/2017

TGFB1 levels have been studied as potential biomarkers for diseases like cancer and fibrosis, aiding in diagnosis and monitoring disease progression.

In what ways does TGFB1 influence wound healing? 05/15/2016

TGFB1 plays a critical role in wound healing by stimulating the formation of new blood vessels, promoting the production of extracellular matrix, and aiding in the migration of cells to the wound site.

How does TGFB1 contribute to fibrosis? 05/06/2016

TGFB1 can induce the production of excessive extracellular matrix proteins, leading to tissue scarring and fibrosis in organs such as the liver, lung, and kidneys.

Customer Reviews (3)

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Reviews
11/16/2021

    The impressive performance of the TGFB1 protein both in ELISA assays and protein electron microscopy structure analysis makes it a highly versatile and recommended choice for scientists across various disciplines.

    03/01/2020

      Its reliability and efficacy in generating high-quality data make it an indispensable tool in the quest for unraveling the mysteries of protein structure and function.

      07/16/2018

        The TGFB1 protein's excellent performance in ELISA ensures accurate and reproducible results, enhancing the reliability of experimental data.

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