Recombinant Human THAP12 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: THAP12-6477H
• Product Overview: PRKRIR MS Standard C13 and N15-labeled recombinant protein (NP_004696) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 87.7 kDa
• AA Sequence: MPNFCAAPNCTRKSTQSDLAFFRFP RDPARCQKWVENCRRADLEDKTPDQ LNKHYRLCAKHFETSMICRTSPYRT VLRDNAIPTIFDLTSHLNNPHSRHR KRIKELSEDKIRTLKQKKIDETSEQ EQKHKETNNSNAQNPSEEEGEGQDE DILPLTLEEKENKEYLKSLFEILIL MGKQNIPLDGHEADEIPEGLFTPDN FQALLECRINSGEEVLRKRFETTAV NTLFCSKTQQRQMLEICESCIREET LREVRDSHFFSIITDDVVDIAGEEH LPVLVRFVDESHNLREEFIGFLPYE ADAEILAVKFHTMITEKWGLNMEYC RGQAYIVSSGFSSRMKVVASRLLEK YPQAIYTLCSSCALNMWLAKSVPVM GVSVALGTIEEVCSFFHRSPQLLLE LDNVISVLFQNSKERGKELKEICHS QWTGRHDAFEILVELLQALVLCLDG INSDTNIRWNNYIAGRAFVLCSAVS DFDFIVTVVVLKNVLSFTRAFGKNL QGQTSDVFFAAGSLTAVLHSLNEVM ENIEVYHEFWFEEATNLATKLDIQM KLPGKFRRAHQGNLESQLTSESYYK ETLSVPTVEHIIQELKDIFSEQHLK ALKCLSLVPSVMGQLKFNTSEEHHA DMYRSDLPNPDTLSAELHCWRIKWK HRGKDIELPSTIYEALHLPDIKFFP NVYALLKVLCILPVMKVENERYENG RKRLKAYLRNTLTDQRSSNLALLNI NFDIKHDLDLMVDTYIKLYTSKSEL PTDNSETVENTTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: THAP12 THAP domain containing 12 [ Homo sapiens (human) ]
• Official Symbol: THAP12
• Synonyms: THAP12; THAP domain containing 12; DAP4; THAP0; PRKRIR; P52rIPK; 52 kDa repressor of the inhibitor of the protein kinase; 58 kDa interferon-induced protein kinase-interacting protein; P58IPK-regulatory protein; THAP domain-containing protein 0; THAP domain-containing protein 12; death-associated protein 4; inhibitor of protein kinase PKR; p58IPK-interacting protein; protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor); testicular tissue protein Li 133
• Gene ID: 5612
• mRNA Refseq: NM_004705
• Protein Refseq: NP_004696
• MIM: 607374
• UniProt ID: O43422