Recombinant Human THY1 Protein, His-tagged
Cat.No. : | THY1-139H |
Product Overview : | Recombinant Human THY1 Protein with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The Thy1/CD90 cell surface antigen is a GPI-anchored, developmentally regulated protein involved in signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosis. Thy1/CD90 is highly expressed on the surface of adult neurons and is thought to play a role in modulating adhesive and migratory events, such as neurite extension. Decreased Thy1/CD90 mRNA and protein expression is associated with the development of epithelial ovarian cancer, suggesting a role as a putative tumor suppressor gene of human ovarian cancer. Research studies indicate that Thy1/CD90 knockout mice have impaired cutaneous immune responses and abnormal retinal development. Thy1/CD90 is epigenetically regulated or deregulated in some disease states, such as pulmonary fibrosis. The potentially reversible hypermethylation of the Thy1/CD90 promoter offers the possibility of novel therapeutic options in this disease. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~17 kDa |
AA Sequence : | MQKVTSLTACLVDQSLRLDCRHENT SSSPIQYEFSLTRETKKHVLFGTVG VPEHTYRSRTNFTSKYNMKVLYLSA FTSKDEGTYTCALHHSGHSPPISSQ NVTVLRDKLVKC |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | THY1 Thy-1 cell surface antigen [ Homo sapiens (human) ] |
Official Symbol : | THY1 |
Synonyms : | THY1; Thy-1 cell surface antigen; thy-1 membrane glycoprotein; CD90; CDw90; thy-1 antigen; Thy-1 T-cell antigen; FLJ33325; |
Gene ID : | 7070 |
mRNA Refseq : | NM_006288 |
Protein Refseq : | NP_006279 |
MIM : | 188230 |
UniProt ID : | P04216 |
Products Types
◆ Recombinant Protein | ||
THY1-542H | Recombinant Human Thy1 Protein | +Inquiry |
THY1-5718R | Recombinant Rat THY1 Protein, His (Fc)-Avi-tagged | +Inquiry |
THY1-4523R | Recombinant Rhesus Macaque THY1 Protein, His (Fc)-Avi-tagged | +Inquiry |
THY1-541H | Recombinant Human Thy1 Protein, Fc-tagged | +Inquiry |
THY1-657H | Recombinant Human THY1 Protein (Met1-Cys130), His-tagged | +Inquiry |
◆ Lysates | ||
THY1-1297RCL | Recombinant Rat THY1 cell lysate | +Inquiry |
THY1-2384MCL | Recombinant Mouse THY1 cell lysate | +Inquiry |
THY1-952CCL | Recombinant Cynomolgus THY1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket