"TIMP3" Related Products

Expand
Expand
Expand

Recombinant Human TIMP3 protein, His-tagged

Cat.No.: TIMP3-852H
Product Overview: Recombinant Human TIMP3(Cys24-Pro211) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Source: E. coli
Species: Human
Tag: His
Form: Lyophilized from a 0.2 µm filtered PBS solution (pH 7.4).
Molecular Mass: 23.4 kDa
Purity: Purity: >90%, as determined by SDS-PAGE under reducing conditions and visualized by Coomassie blue staining.
Applications: ELISA, Western blotting, Dot Blotting, Immunogen, Protein Array, Function Assay, etc. Before use, heat the WBC control at 95 centigrade for 5 minutes. Spin down the sample and load 5 µL per lane onto SDS-PAGE gel.
Storage: Upon arrival, the protein may be stored for 2 weeks at 4 centigrade. For long term storage, it is recommended to store at -20 centigrade or -80 centigrade in appropriate aliquots. Avoid repeated freeze-thaw cycles.
Reconstitution: Briefly spin the vial and bring the contents to the bottom prior to opening. It is recommended to reconstitute at 0.5~1.0 mg/mL with sterile deionized water or PBS.
Gene Name: TIMP3 TIMP metallopeptidase inhibitor 3 [ Homo sapiens ]
Official Symbol: TIMP3
Synonyms: TIMP3; TIMP metallopeptidase inhibitor 3; SFD, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); metalloproteinase inhibitor 3; TIMP-3; MIG-5 protein; protein MIG-5; tissue inhibitor of metalloproteinases 3; SFD; K222; K222TA2; HSMRK222;
Gene ID: 7078
mRNA Refseq: NM_000362
Protein Refseq: NP_000353
MIM: 188826
UniProt ID: P35625
Chromosome Location: 22q12.3
Pathway: Endochondral Ossification, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
Function: enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity; protein binding;

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.