Recombinant Human TIPIN, His-tagged

• Cat.No.: TIPIN-2342H
• Product Overview: Recombinant human TIPIN, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: TIPIN belongs to the CSM3 family. This protein is required for normal progression of S-phase and important for cell survival after DNA damage or replication stress. TIPIN may be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 36.9kDa
• Protein length: 324 aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLEPQEN GVIDLPDYEH VEDETFPPFP PPASPERQDG EGTEPDEESG NGAPVPVPPK RTVKRNIPKLDAQRLISERG LPALRHVFDK AKFKGKGHEA EDLKMLIRHM EHWAHRLFPK LQFEDFIDRV EYLGSKKEVQ TCLKRIRLDL PILHEDFVSN NDEVAENNEH DVTSTELDPF LTNLSESEMF ASELSRSLTE EQQQRIERNK QLALERRQAK LLSNSQTLGN DMLMNTPRAH TVEEVNTDEDQKEESNGLNE DILDNPCNDA IANTLNEEET LLDQSFKNVQ QQLDATSRNI TEAR
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: TIPIN TIMELESS interacting protein [ Homo sapiens ]
• Official Symbol: TIPIN
• Synonyms: TIPIN; TIMELESS interacting protein; TIMELESS-interacting protein; CSM3 homolog (S. cerevisiae); FLJ20516; CSM3 homolog
• Gene ID: 54962
• mRNA Refseq: NM_017858
• Protein Refseq: NP_060328
• MIM: 610716
• UniProt ID: Q9BVW5
• Chromosome Location: 15q22.31
• Function: protein binding