| Description : |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
79.8 kDa |
| AA Sequence : |
MYPQGRHPTPLQSGQPFKFSILEIC DRIKEEFQFLQAQYHSLKLECEKLA SEKTEMQRHYVMYYEMSYGLNIEMH KQAEIVKRLSGICAQIIPFLTQEHQ QQVLQAVERAKQVTVGELNSLIGQQ LQPLSHHAPPVPLTPRPAGLVGGSA TGLLALSGALAAQAQLAAAVKEDRA GVEAEGSRVERAPSRSASPSPPESL VEEERPSGPGGGGKQRADEKEPSGP YESDEDKSDYNLVVDEDQPSEPPSP ATTPCGKVPICIPARRDLVDSPASL ASSLGSPLPRAKELILNDLPASTPA SKSCDSSPPQDASTPGPSSASHLCQ LAAKPAPSTDSVALRSPLTLSSPFT TSFSLGSHSTLNGDLSVPSSYVSLH LSPQVSSSVVYGRSPVMAFESHPHL RGSSVSSSLPSIPGGKPAYSFHVSA DGQMQPVPFPSDALVGAGIPRHARQ LHTLAHGEVVCAVTISGSTQHVYTG GKGCVKVWDVGQPGAKTPVAQLDCL NRDNYIRSCKLLPDGRSLIVGGEAS TLSIWDLAAPTPRIKAELTSSAPAC YALAVSPDAKVCFSCCSDGNIVVWD LQNQTMVRQFQGHTDGASCIDISDY GTRLWTGGLDNTVRCWDLREGRQLQ QHDFSSQIFSLGHCPNQDWLAVGME SSNVEILHVRKPEKYQLHLHESCVL SLKFASCGRWFVSTGKDNLLNAWRT PYGASIFQSKESSSVLSCDISRNNK YIVTGSGDKKATVYEVVYTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
