Recombinant Human TLK1 Protein, MYC/DDK-tagged

• Cat.No.: TLK1-1107H
• Product Overview: Recombinant human TLK1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 86.5 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TLK1 tousled-like kinase 1 [ Homo sapiens ]
• Official Symbol: TLK1
• Synonyms: PKU-beta; PKU-beta
• Gene ID: 9874
• mRNA Refseq: NM_001136554
• Protein Refseq: NP_001130026
• MIM: 608438
• UniProt ID: Q9UKI8