Description : |
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
85.3 kDa |
AA Sequence : |
MMEELHSLDPRRQELLEARFTGVGV SKGPLNSESSNQSLCSVGSLSDKEV ETPEKKQNDQRNRKRKAEPYETSQG KGTPRGHKISDYFEFAGGSAPGTSP GRSVPPVARSSPQHSLSNPLPRRVE QPLYGLDGSAAKEATEEQSALPTLM SVMLAKPRLDTEQLAQRGAGLCFTF VSAQQNSPSSTGSGNTEHSCSSQKQ ISIQHRQTQSDLTIEKISALENSKN SDLEKKEGRIDDLLRANCDLRRQID EQQKMLEKYKERLNRCVTMSKKLLI EKSKQEKMACRDKSMQDRLRLGHFT TVRHGASFTEQWTDGYAFQNLIKQQ ERINSQREEIERQRKMLAKRKPPAM GQAPPATNEQKQRKSKTNGAENETL TLAEYHEQEEIFKLRLGHLKKEEAE IQAELERLERVRNLHIRELKRIHNE DNSQFKDHPTLNDRYLLLHLLGRGG FSEVYKAFDLTEQRYVAVKIHQLNK NWRDEKKENYHKHACREYRIHKELD HPRIVKLYDYFSLDTDSFCTVLEYC EGNDLDFYLKQHKLMSEKEARSIIM QIVNALKYLNEIKPPIIHYDLKPGN ILLVNGTACGEIKITDFGLSKIMDD DSYNSVDGMELTSQGAGTYWYLPPE CFVVGKEPPKISNKVDVWSVGVIFY QCLYGRKPFGHNQSQQDILQENTIL KATEVQFPPKPVVTPEAKAFIRRCL AYRKEDRIDVQQLACDPYLLPHIRK SVSTSSPAGAAIASTSGASNNSSSN TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |