Recombinant Human TMED9 Protein (40-197 aa), GST-tagged

• Cat.No.: TMED9-1208H
• Product Overview: Recombinant Human TMED9 Protein (40-197 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Partial.

Specification

• Description: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to mbranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi mbranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular mbranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 45.5 kDa
• Protein length: 40-197 aa
• AA Sequence: FHIGETEKKCFIEEIPDETMVIGNY RTQLYDKQREEYQPATPGLGMFVEV KDPEDKVILARQYGSEGRFTFTSHT PGEHQICLHSNSTKFSLFAGGMLRV HLDIQVGEHANDYAEIAAKDKLSEL QLRVRQLVEQVEQIQKEQNYQRWRE ERFRQTSE
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: TMED9 transmembrane p24 trafficking protein 9 [ Homo sapiens (human) ]
• Official Symbol: TMED9
• Synonyms: p25; GMP25; p24a2; HSGP25L2G; p24alpha2
• Gene ID: 54732
• mRNA Refseq: NM_017510
• Protein Refseq: NP_059980
• UniProt ID: Q9BVK6