Recombinant Human TMEM189 Protein, MYC/DDK-tagged

• Cat.No.: TMEM189-269H
• Product Overview: Recombinant Human TMEM189 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 42 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TMEM189 transmembrane protein 189 [ Homo sapiens ]
• Official Symbol: TMEM189
• Synonyms: KUA; TMEM189; transmembrane protein 189
• Gene ID: 387521
• mRNA Refseq: NM_199129
• Protein Refseq: NP_954580
• UniProt ID: A5PLL7