Recombinant Human TMX3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human TMX3 Protein, Myc/DDK-tagged, C13 and N15-labeled

TMX3 Related Products

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Cat.No. : TMX3-5546H
Product Overview : TMX3 MS Standard C13 and N15-labeled recombinant protein (NP_061895) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 51.9 kDa
AA Sequence : MAAWKSWTAL RLCATVVVLD MVVCKGFVED LDESFKENRN DDIWLVDFYA PWCGHCKKLE PIWNEVGLEM KSIGSPVKVG KMDATSYSSI ASEFGVRGYP TIKLLKGDLA YNYRGPRTKD DIIEFAHRVS GALIRPLPSQ QMFEHMQKRH RVFFVYVGGE SPLKEKYIDA ASELIVYTYF FSASEEVVPE YVTLKEMPAV LVFKDETYFV YDEYEDGDLS SWINRERFQN YLAMDGFLLY ELGDTGKLVA LAVIDEKNTS VEHTRLKSII QEVARDYRDL FHRDFQFGHM DGNDYINTLL MDELTVPTVV VLNTSNQQYF LLDRQIKNVE DMVQFINNIL DGTVEAQGGD SILQRLKRIV FDAKSTIVSI FKSSPLMGCF LFGLPLGVIS IMCYGIYTAD TDGGYIEERY EVSKSENENQ EQIEESKEQQ EPSSGGSVVP TVQEPKDVLE KKKDTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TMX3 thioredoxin related transmembrane protein 3 [ Homo sapiens (human) ]
Official Symbol : TMX3
Synonyms : TMX3; thioredoxin related transmembrane protein 3; PDIA13; TXNDC10; protein disulfide-isomerase TMX3; protein disulfide isomerase family A, member 13; thioredoxin domain containing 10; thioredoxin domain-containing protein 10; EC 5.3.4.1
Gene ID : 54495
mRNA Refseq : NM_019022
Protein Refseq : NP_061895
MIM : 616102
UniProt ID : Q96JJ7

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