Recombinant Human TNF Protein TNF-51H

Recombinant Human TNF Protein

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Cat.No. : TNF-51H Optional Service: Optional requirements on this protein
Product Overview : This recombinant protein contains full length of Human TNF-α without tag was expressed in E. coli.
Description : This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Source : E. coli
Species : Human
Form : Affinity purified, liquid
Molecular Mass : 18.55 kDa
Purity : >95% pure by SDS-PAGE
Applications : Suitable for use in ELISA, WB and other immune tests
Storage : Upon receipt, store at 2-8 centigrade.
Storage Buffer : Phosphate saline, pH 8, and 8 M Urea
Gene Name : TNF tumor necrosis factor [ Homo sapiens (human) ]
Official Symbol : TNF
Synonyms : TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; tumor necrosis factor; APC1 protein; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha
Gene ID : 7124
mRNA Refseq : NM_000594
Protein Refseq : NP_000585
MIM : 191160
UniProt ID : P01375
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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