Recombinant Human TNFRSF18 protein, Mouse IgG2a Fc-tagged, low endotoxin
Cat.No. : | TNFRSF18-330H |
Product Overview : | Recombinant Human TNFRSF18 protein (Gln26-Glu161)(low endotoxin), fused to Mouse IgG2a Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
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Species : | Human |
Source : | HEK293 |
Tag : | mIgG2a |
ProteinLength : | 136 |
Description : | Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 41.4 kDa. The protein migrates as 46-49 kDa and 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin : | Less than 0.1 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name | TNFRSF18 |
Official Symbol | TNFRSF18 |
Synonyms | TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; AITR; CD357; GITR; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; GITR-D |
Gene ID | 8784 |
mRNA Refseq | NM_004195 |
Protein Refseq | NP_004186 |
MIM | 603905 |
UniProt ID | Q9Y5U5 |
◆ Native Proteins | ||
GPIIbIIIa-73H | Native Human GPIIbIIIa | +Inquiry |
Collagen type I-02H | Native Human Collagen type I Protein | +Inquiry |
Collagen-46M | Native Mouse Collagen protein | +Inquiry |
Plasmin-250H | Active Native Human Plasmin | +Inquiry |
Lectin-1801L | Active Native Lycopersicon Esculentum Lectin Protein, Biotinylated | +Inquiry |
◆ Cell & Tissue Lysates | ||
CHKB-7534HCL | Recombinant Human CHKB 293 Cell Lysate | +Inquiry |
EFCAB4A-6708HCL | Recombinant Human EFCAB4A 293 Cell Lysate | +Inquiry |
NDUFB3-3906HCL | Recombinant Human NDUFB3 293 Cell Lysate | +Inquiry |
LYAR-1040HCL | Recombinant Human LYAR cell lysate | +Inquiry |
SMR3A-1652HCL | Recombinant Human SMR3A 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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