Recombinant Human TNFSF18 protein, His-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human TNFSF18 protein, His-tagged

Recombinant Human TNFSF18 protein, His-tagged

TNFSF18 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : TNFSF18-722H
Product Overview : Recombinant Human TNFSF18 (Gln50-Ser177) protein was fused to His-tag at N-terminus and expressed in human 293 cells (HEK293).
Description : Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18/GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18/GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Gln50
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 20.5 kDa. The protein migrates as 23 kDa and 26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Gln50-Ser177
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
SDS-PAGE of TNFSF18-722H :

Human GITR Ligand, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA of TNFSF18-722H :

Immobilized Human GITR Ligand, His Tag at 2 μg/mL (100 μL/well) can bind Human GITR, Fc Tag with a linear range of 0.1-4 ng/mL (QC tested).

Bioactivity-ELISA :

Immobilized Human GITR Ligand, His Tag at 2 μg/mL (100 μL/well) can bind Human GITR, Mouse IgG2a Fc Tag, low endotoxin with a linear range of 0.2-8 ng/mL (Routinely tested).

Gene Name : TNFSF18
Official Symbol : TNFSF18
Synonyms : TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18; AITRL; hGITRL; TL6; AITR ligand; GITR ligand; activation-inducible TNF-related ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; GITRL; MGC138237
Gene ID : 8995
mRNA Refseq : NM_005092
Protein Refseq : NP_005083
MIM : 603898
UniProt ID : Q9UNG2

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.