Recombinant Human TNFSF4 Protein, Fc-tagged, FITC conjugated

Cat.No. : TNFSF4-491HF
Product Overview : FITC conjugated recombinant human TNFSF4(Gln51-Leu183) fused with Fc region of human IgG1 at the N-terminus was expressed in HEK293.
Availability August 05, 2025
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Species : Human
Source : HEK293
Tag : Fc
Protein Length : Gln51-Leu183, 412
Description : OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Form : Lyophilized
Molecular Mass : 46.6 kDa
N-terminal Sequence Analysis : Glu
Endotoxin : < 1.0 EU/ μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE
Characteristic : Disulfide-linked homodimer
Labeled with FITC via amines
Excitation source: 488 nm spectral line, argon-ion laser
Excitation Wavelength: 488 nm
Emission Wavelength: 535 nm
Stability : Samples are stable for up to 12 months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Shipping : Shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Conjugation : FITC
Gene Name TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 [ Homo sapiens ]
Official Symbol TNFSF4
Synonyms TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; tax transcriptionally activated glycoprotein 1, 34kD , TXGP1; tumor necrosis factor ligand superfamily member 4; CD252; gp34; OX 40L; OX40L; CD134 ligand; glycoprotein Gp34; OX40 antigen ligand; TAX transcriptionally-activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 (34kD); GP34; OX4OL; TXGP1; CD134L; OX-40L;
Gene ID 7292
mRNA Refseq NM_003326
Protein Refseq NP_003317
MIM 603594
UniProt ID P23510

Not For Human Consumption!

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