Recombinant Human TNPO1 Protein, His-tagged

• Cat.No.: TNPO1-342H
• Product Overview: Recombinant Human TNPO1(Lys626~Val836) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 24.7kDa
• Identity: Reconstitute in PBS or others
• Protein length: Lys626~Val836
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: TNPO1 transportin 1 [ Homo sapiens ]
• Official Symbol: TNPO1
• Synonyms: TNPO1; transportin 1; karyopherin (importin) beta 2 , KPNB2; transportin-1; importin 2; IPO2; MIP; MIP1; TRN; importin beta 2; importin beta-2; karyopherin beta-2; M9 region interaction protein; karyopherin (importin) beta 2; KPNB2
• Gene ID: 3842
• mRNA Refseq: NM_002270
• Protein Refseq: NP_002261
• MIM: 602901
• UniProt ID: Q92973