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Recombinant Human TPBG protein, MYC/DDK-tagged

Cat.No. : TPBG-190H
Product Overview : Recombinant Human TPBG fused with MYC/DDK tag at C-terminal was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 45.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Notes : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TPBG trophoblast glycoprotein [ Homo sapiens ]
Official Symbol : TPBG
Synonyms : TPBG; trophoblast glycoprotein; 5T4; 5T4 AG; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein; 5T4 oncofetal trophoblast glycoprotein; M6P1; 5T4AG;
Gene ID : 7162
mRNA Refseq : NM_006670
Protein Refseq : NP_006661
MIM : 190920
UniProt ID : Q13641
Chromosome Location : 6q14-q15

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the significance of TPBG in cancer diagnosis or prognosis? 01/23/2022

Elevated TPBG levels can serve as a biomarker and may correlate with poor prognosis in some cancers.

Are there any known post-translational modifications of TPBG, and what are their effects? 07/08/2021

While the post-translational modifications of TPBG are not fully elucidated, they could affect its localization, stability, and interactions with other proteins.

What known proteins interact with TPBG, influencing its function? 03/15/2021

Specific interacting partners of TPBG that significantly influence its function are still under investigation.

How does TPBG expression change in cancerous cells? 03/01/2021

TPBG expression is often upregulated in various types of cancer cells.

How does TPBG contribute to the immune evasion of cancer cells? 06/27/2020

TPBG might contribute to immune evasion by interacting with immune cells and modulating immune responses.

What is the primary biological role of TPBG in normal cells? 02/09/2020

TPBG plays roles in cell adhesion, migration, and proliferation in normal cells.

What potential therapeutic interventions could target TPBG? 07/14/2019

Targeting TPBG could provide a therapeutic avenue, particularly in cancers where it is overexpressed, potentially improving immune response and treatment outcomes.

Customer Reviews (3)

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Reviews
09/01/2022

    Reliable and reproducible results.

    04/28/2021

      Worked well for Western blot.

      06/17/2018

        Great for research purposes.

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